50/60S set is a blend of the best of the 54 and 64 sets combined in one. This is one of my most versatile and popular sets of pickups. They have a tight punchy sound on the E, A and D strings and a beautiful compression and bloom on the G, B and E strings. These sound great in any Strat wood combination because of their beautiful overall string and pickup balance. The 50/60S has the John Mayer tone written all over them.